publications

2025

1. Forthcoming

   Use of Electronic Patient Record Systems for Rapid Response to an MHRA Public Assessment Report: Retrospective Observational Study (Preprint)

   Dylan Whitaker, Matthew Wilson, Aoife Hughes, and 2 more authors

   JMIR Formative Research, Aug 2025

   Open DOI
2. BJA Open

   Effects of patient-controlled analgesia on patient outcomes after laparoscopic nephrectomy

   Nafeesa Abdul Nazar, Sindhu Sankaran, Dylan Whitaker, and 8 more authors

   2026/01/29 2025

   Open DOI
3. Conference

   Comparison of as-required versus regular weaning inhaled salbutamol post-acute wheezing

   Kah Wee Teo, Dylan Whitaker, and Karena Fraser

   2025

   Abstract Open DOI

   Background: Children often receive regular weaning doses of inhaled salbutamol upon discharge following acute wheezing attacks, despite limited evidence supporting this practice. The Global Initiative for Asthma recommends using relievers as needed upon discharge. In Cambridge University Hospitals, the regular weaning inhaled salbutamol (RWIS) regimen was replaced by an as-required inhaled salbutamol (ARIS) regimen on 12-Sep-2023. Objectives: To evaluate the safety of the ARIS regimen compared to the RWIS regimen post-acute wheezing attacks Methods: A single-center retrospective observational cohort study was conducted, comparing the number of re-presentations to the Paediatric Emergency Department (PED) within 28 days, among children aged 0-17 years presenting to PED with asthma or viral-induced wheeze between 12-Sep and 5-Dec (84 days) in 2021, 2022, and 2023. Statistical significance was assessed using odds ratios and the chi-squared test of independence Results: In year 2021, 2022, and 2023, there were 333, 260, and 322 PED presentations for acute wheezing, respectively, with 56, 49, and 49 re-presentations within 28 days. The odds ratio for PED re-presentations with the ARIS regimen was 0.834 (0.576 – 1.208, p value 0.337) Conclusion: The use of the ARIS regimen post-acute wheezing attacks resulted in a lower rate of PED re-presentations, although not statistically significant. This suggests that the ARIS regimen is as safe as the conventionally used RWIS regimen. When used correctly, this approach can prevent overuse of salbutamol, mitigate the masking effect of deterioration, and empower patients to manage their asthma effectively.

4. Preprint

   Use of Electronic Patient Record Systems for Rapid Response to an MHRA Public Assessment Report 

   Dylan Whitaker, Matthew Wilson, Aoife Hughes, and 2 more authors

   JMIR Preprints, Aug 2025

   Open DOI
5. BMJ ADC

   Retrospective cohort observational study to assess the impact of as-required versus regular weaning inhaled salbutamol postattack wheeze plan in paediatric acute wheeze

   Dylan Whitaker, Kah Wee Teo, and Karena Fraser

   Archives of Disease in Childhood, Mar 2025

   Open DOI

2024

1. BMJ Case Reports

   Hyperkalaemic cardiac arrest in Angelman’s syndrome following suxamethonium

   Dylan Whitaker, Heba Yousef, and Augusto Mauro

   BMJ Case Reports, Dec 2024

   Open DOI